Our first publication1 spotlights Demodex; the microscopic arachnids known to infest mammalian eyelashes and cause blepharitis. The most important characteristics of Demodex are described with signposting to a full range of references to allow in-depth learning. An explanation for established links between blepharitis and a range of allergic, respiratory and dermatological conditions, known as ‘The Allergic March’ is proposed, and delving into entomology exposes some clinical signs which may indicate Demodex presence. This may interest dermatologists, ENT and allergy specialists, general physicians and pharmacists alike.
The rationale for a non-pharmacological approach, using just petroleum jelly on the eyelashes at night, to prevent Demodex from mating, is explained, and how this mode of treatment could become a potential first-line approach for managing blepharitis, and related allergic conditions including rhinitis and asthma. This paper describes a dramatic fall in anti-allergy medications requested by the three volunteers for whom prescribing data were available. However, only formal clinical trials will confirm this phenomenon and the safety and effectiveness of the treatment. We also address the current confusion over the pharmaceutical properties of petroleum jelly, for people who may be concerned.
We hope you find it interesting and helpful.
- Senior-Fletcher DE. Reducing ocular Demodex using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated prescribing:
a hypothesis. Frontiers in Allergy 2025;6. DOI=10.3389/falgy.2025.1576102. ↩︎